hydroxyethylcellulose gel containing microencapsulated extract of arrabidaea chica

摘要

hydroxyethylcellulose gel containing microencapsulated extract of arrabidaea chica the present invention patent deals with technological development for optimization semi-solid formulation (gel) for topical application, using microencapsulation conditions, by spray drying, containing as an active agent the extract of arrabidaea chica . hydroxyethylcellulose was used as a polymer for the drying process. the obtaining of the microencapsulated extract of the pariri occurred from the solubilization of the crude extract (obtained by percolation) in a 70% (v / v) ethanolic solution and the addition of hec in the extract was in the concentration of 1.5% (w / v ). the operational parameters were: drying air inlet temperature (tge = 100ºc), drying air outlet temperature (tgs = 78ºc), extract feed flow rate (wsusp = 0.2 l / h), air pressure atomization (patm = 6 bar), atomization air flow (watm = 20 lpm) and drying air flow of 60 m3 / h. the studies carried out consisted of the physical-chemical characterization of the microencapsulated extract and the development and evaluation of the formulation without the addition of another thickening agent; preliminary gel stability. thus, the microcapsules containing the extract of a. chica was favorable as an intermediate product and has advantages in the final production of semi-solid gels.