methods to produce cd4 / cd8 double-positive cells and cd8 single-positive cells, cell population, and reagent to separate hematopoietic progenitor cells.

摘要

the present invention provides a method for producing cd4 / cd8 double-positive cells, the method comprising the following steps. step 1: a step to separate, from the cell population containing hematopoietic progenitor cells, cells that express one or more molecules selected from the group consisting of cd24, cd62l, cd90, cd143, cd263, notch3, cd32, cd39, cd49a , cd164, cd317, cd200 and cd218a; and step 2: a step to differentiate the cells separated in step 1 into cd4 / cd8 double-positive cells.