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method to improve physical performance and treatment method to improve physical or mental performance

机译:改善身体表现的方法和治疗方法

摘要

it is a human food supplement that comprises theacrine and optionally other compounds that modulate the effects of theacrine. Uses for the theatrine-containing supplement include improving at least one among mood, energy, focus, concentration or sexual desire or a reduction of at least one among anxiety or fatigue. a synergistic composition comprises co-administration of theacrine and caffeine, with co-administered caffeine reducing oral theacrine clearance (cl / f) and oral volume of distribution (vd / f). in addition, coadministered caffeine increases the area under the (auc) time curve of plasma theacrine concentration, and increases the maximum plasma concentration of theacrine (cmax) compared to pharmacokinetic parameters when teacrine is administered alone.
机译:它是一种人类食品补充剂,其中包含茶碱和其他可调节茶碱作用的化合物。含茶碱的补充剂的用途包括改善情绪,精力,注意力,注意力或性欲中的至少一种,或减少焦虑或疲劳中的至少一种。协同组合物包括茶碱和咖啡因的共同给药,咖啡因的共同给药降低口服茶碱的清除率(cl / f)和口服分布体积(vd / f)。此外,与单独使用茶碱时的药代动力学参数相比,共同给药的咖啡因会增加血浆茶碱浓度的(auc)时间曲线下的面积,并增加茶碱的最大血浆浓度(cmax)。

著录项

  • 公开/公告号BR112019024373A2

    专利类型

  • 公开/公告日2020-06-09

    原文格式PDF

  • 申请/专利权人 ORTHO-NUTRA LLC;

    申请/专利号BR20191124373

  • 申请日2018-05-16

  • 分类号A61K31/522;A61P21;

  • 国家 BR

  • 入库时间 2022-08-21 11:18:22

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