PYRIDIDNE-SULFONAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS

摘要

The invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein the variables Y¹-Y⁶, X, Z, Z¹, Z², R²-R³, and R⁶ have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions. The compounds have sodium channel blocking activity that are useful for treating sodium channel-mediated diseases, in particular for treating pain