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METHODS OF MONITORING, TREATING, AND PREVENTING RENAL INFLAMMATION ASSOCIATED WITH NEPHROTOXICITY
METHODS OF MONITORING, TREATING, AND PREVENTING RENAL INFLAMMATION ASSOCIATED WITH NEPHROTOXICITY
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机译:监测,预防和预防与肾毒性相关的肾炎的方法
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摘要
The invention provides methods of monitoring development of renal inflammation in a subject following administration of a nephrotoxic agent. The methods involve analyzing levels of one or more UDP-hexoses, such as UDP-glucose, UDP-galactose, UDP-glucuronic acid, N-acetyl-UDP-glucosamine, or N-acetyl-UDP-galactosamine, in a sample from the subject. The invention also provides methods of treating or preventing renal inflammation in a subject who has been given a nephrotoxic agent by providing a P2Y 14 receptor antagonist to the subject.
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