ANTI-H7N9 FULLY HUMAN MONOCLONAL ANTIBODY HIG311, PREPARATION METHOD THEREFOR, AND APPLICATION

摘要

Provided are an anti-H7N9 fully human monoclonal antibody hIg311, a preparation method therefor, and an application. The fully human monoclonal antibody hIg311 is rapidly screened by means of a memory B cell PCR method, and does not contain any murine component. The antibody targets the hemagglutinin (HA) of the H7N9 virus, has anti-H7N9 virus infection neutralizing activity, does not have toxic side effects of anti-mouse antibodies etc., has better biocompatibility, and is more suitable and has more potential to be a macromolecular drug which treats influenza viruses.