RECOMBINANT VECTOR FOR EXPRESSING VIRUS-LIKE PARTICLES IN PLANT AND METHOD FOR PREPARATION OF VACCINE COMPOSITION CONTAINING CIRCOVIRUS-LIKE PARTICLES BY USING SAME

摘要

The present invention relates to a technique of preparing a vaccine composition from PCV2 isolated from a plant transformed with a chlorophyll-targeting recombinant vector for expression in plants and provides a recombinant vector carrying a polynucleotide coding for a recombinant protein in which a chlorophyll-targeting protein and a PCV2 capsid protein are fused to each other. In addition, provided are a transgenic plant transformed with the recombinant vector, a method for isolating and purifying a target protein from the transgenic plant, a method for preparing a vaccine composition containing virus-like particles by using same, and a vaccine composition prepared by the preparation method.