Recombinant vector expressing virus-like particles in plants and methods of preparing vaccine compositions comprising circovirus-like particles using the same

摘要

The present invention relates to a technology for preparing a vaccine composition for PCV2 isolated from a plant transformed using a recombinant vector for plant expression targeted to chloroplasts. Recombinant vectors comprising nucleotides are provided. In addition, a transgenic plant transformed by the recombinant vector, a method for separating and purifying a target protein from the transgenic plant, a method for preparing a vaccine composition comprising virus-like particles using the same, and a vaccine composition according to the manufacturing method, etc. this is provided