首页> 外国专利> METHOD FOR PREPARING HETEROGENEOUS HEMATOPOIETIC STEM/PROGENITOR CELLS BY NON-MOBILIZED PERIPHERAL BLOOD

METHOD FOR PREPARING HETEROGENEOUS HEMATOPOIETIC STEM/PROGENITOR CELLS BY NON-MOBILIZED PERIPHERAL BLOOD

机译:非流动化外周血制备异质造血干/祖细胞的方法

摘要

Provided is a method for preparing heterogeneous hematopoietic stem/progenitor cells by non-mobilized peripheral blood. According to the method, a capsule culture system is used for capturing and amplifying rare hematopoietic stem/progenitor cells in non-mobilized peripheral blood, and heterogeneous hematopoietic stem/progenitor cell clones are prepared. By capturing the rare heterogeneous stem cells in the non-mobilized peripheral blood, the existence of the heterogeneous hematopoietic stem/progenitor cells in the non-mobilized peripheral blood is verified morphologically. The method has characteristics of hematopoietic reconstruction, drug development, transplantation and immunotherapy, cell types of gene editing and the like.
机译:提供了一种通过未动员的外周血制备异种造血干/祖细胞的方法。根据该方法,将胶囊培养系统用于捕获和扩增未动员的外周血中的稀有造血干/祖细胞,并制备异种造血干/祖细胞克隆。通过捕获未动员的外周血中的稀有异种干细胞,形态学上证实了未动员的外周血中异种造血干/祖细胞的存在。该方法具有造血重建,药物开发,移植和免疫疗法,基因编辑的细胞类型等特征。

著录项

  • 公开/公告号WO2020147272A9

    专利类型

  • 公开/公告日2020-11-05

    原文格式PDF

  • 申请/专利权人 ZHEJIANG UNIVERSITY;

    申请/专利号WO2019CN94977

  • 发明设计人 HUANG HE;XU YULIN;YU XIAOHONG;

    申请日2019-07-08

  • 分类号A61K35/28;A61P35;C12N5/0789;

  • 国家 WO

  • 入库时间 2022-08-21 11:10:09

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