Manufacturing method of heterogeneous hematopoietic stem cell and progenitor cell using non mobilized peripheral blood

摘要

Problem to be solved: to provide a method for producing non-uniform hematopoietic stem cells and progenitor cells using non mobilized peripheral blood, and to capture and multiply rare hematopoietic stem cells and progenitor cells in non mobilized peripheral blood in a microcapsule culture system, and to amplify the heterologous hematopoietic stem cells and progenitor cells.The present invention analyzes the presence of heterogeneous hematopoietic stem cells and progenitor cells in non mobilized peripheral blood by capturing rare heterologous stem cells in non mobilized peripheral blood.The method of the present invention has features such as hematopoietic reconstitution, drug development, transplantation and immunotherapy, and cell type of gene editing.The method of the present invention provides a reliable source of cells to obtain the patient's unique functional hematopoietic stem cells and actively promotes clinical applications of non mobilized hematopoietic stem cells and progenitor cells.Selection