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METHOD FOR TREATMENT OF ROSACEA INCLUDING PATIENT REPORTED OUTCOMES THEREOF

机译:包括患者报告结果在内的酒渣鼻的治疗方法

摘要

A regimen is described for the therapeutic treatment of rosacea including topically applying to the skin of a subject in need of the treatment a pharmaceutical composition. The pharmaceutical composition includes about 1% w/w to about 10% w/w benzoyl peroxide as an active ingredient, and a pharmaceutically acceptable carrier or excipient. The benzoyl peroxide is the only active ingredient in said pharmaceutical composition, and the pharmaceutical composition is applied once daily for a period of at least about 2 weeks, about 4 weeks, about 8 weeks or about 12 weeks. A decrease in Patient Assessment of Papulopustular Rosacea Signs and Symptoms (PAPSS) is at least about 40% after treatment with the pharmaceutical composition for about 4 weeks, and a decrease in Patient Assessment of Papulopustular Rosacea Impacts (PAPI) is from about 60% to about 70% after treatment with the pharmaceutical composition for at least about 8 weeks.
机译:描述了用于治疗酒渣鼻的方案,该方案包括将药物组合物局部施用于需要该治疗的受试者的皮肤。该药物组合物包含约1%w / w至约10%w / w的过氧化苯甲酰作为活性成分,以及药学上可接受的载体或赋形剂。过氧化苯甲酰是所述药物组合物中的唯一活性成分,并且该药物组合物每天一次施用至少约2周,约4周,约8周或约12周的时间。用药物组合物治疗约4周后,对丘疹性酒渣鼻症状和体征(PAPSS)的患者评估减少至少约40%,对患者的丘疹性酒渣鼻影响(PAPI)的评估从约60%降低至用药物组合物治疗至少约8周后约70%。

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