DNA RNA Cas Cas DNA Composition for cleaving a target DNA comprising a guideRNA specific for the target DNA and Cas protein-encoding nucleicacid or Cas protein and use thereof

摘要

The present invention relates to targeted genomic correction in eukaryotic cells or organisms. More specifically, the present invention relates to compositions for cleaving target DNA in eukaryotic cells or organisms, and uses thereof, comprising nucleic acids or Cas proteins encoding guide RNAs and Cas proteins specific for the target DNA.