Biosensors Produced from Enzymes with Reduced Solubility and Methods for Producing and Using Them

摘要

Multi-use biosensors comprising enzymes modified to reduce solubility are disclosed; The multi-use biosensors are used to detect analytes in fluid biological samples, which also maintain their enzymatic activity after many uses. A multi-sensor array is disclosed that includes a plurality of biosensors. Also disclosed are methods of creating and using these devices.