首页> 外国专利> Composition for preventing treating or improving obesity comprising Jaceosidin

Composition for preventing treating or improving obesity comprising Jaceosidin

机译:用于预防或改善肥胖的组合物,其包含杰西苷

摘要

The present invention relates to a composition for preventing, treating or alleviating obesity containing jaceosidin as an active component. The jaceosidin has an effect of inhibiting differentiation of adipocytes and reducing lipid accumulation in cells. In addition, the jaceosidin exhibits an excellent anti-obesity effect by inhibiting the expression of peroxysome proliferator activator receptor gamma (PPARγ) and CCAAT-enhancer binding protein alpha (C/EBPa) and adiponectin, which are transcription factors involved in adipocyte formation and differentiation. Therefore, jaceosidin of the present invention can be usefully used as a pharmaceutical composition and health functional food for preventing, treating or alleviating obesity.
机译:预防,治疗或减轻肥胖症的组合物技术领域本发明涉及一种预防,治疗或减轻肥胖症的组合物,其含有鞘脂苷作为有效成分。鞘磷脂具有抑制脂肪细胞分化和减少细胞中脂质蓄积的作用。此外,剑豆苷通过抑制过氧化物酶体增殖物激活剂受体γ(PPARγ)和CCAAT增强子结合蛋白α(C / EBPa)和脂联素的表达而表现出优异的抗肥胖作用,这是参与脂肪细胞形成和分化的转录因子。因此,本发明的鞘脂苷可以有效地用作预防,治疗或减轻肥胖的药物组合物和保健功能食品。

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