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The method and system for the resolution of bias arising from immeasurable time in the estimation of drug's effects

机译:解决在药物作用评估中因无法估量的时间而产生的偏见的方法和系统

摘要

The present invention relates to a method and a system for solving the skew problem caused by unmeasurable time occurring in a pharmacodynamic study to which a patient-control study design is applied. The present invention calculates the exposure rate of each of the patient group and the control group and a method for estimating the correlation between drug exposure and disease by statistically assigning different weights to patient group data with a history of drug exposure and patient group data without a history of drug exposure. By doing so, we propose a method to grasp the correlation between drug exposure and disease.
机译:本发明涉及一种方法和系统,该方法和系统用于解决在应用了患者对照研究设计的药效学研究中由于不可测量的时间而引起的偏斜问题。本发明计算患者组和对照组中每一个的暴露率,以及通过对具有药物暴露史的患者组数据和患者组数据进行统计分配不同的权重来统计地分配不同的权重,从而估计药物暴露与疾病之间的相关性的方法。药物接触史。通过这样做,我们提出了一种方法来掌握药物暴露与疾病之间的相关性。

著录项

  • 公开/公告号KR20200086158A

    专利类型

  • 公开/公告日2020-07-16

    原文格式PDF

  • 申请/专利权人 성균관대학교산학협력단;

    申请/专利号KR20190002427

  • 发明设计人 신주영;오인선;김혜준;

    申请日2019-01-08

  • 分类号G16H20/10;G16H10/20;G16H10/40;G16H10/60;

  • 国家 KR

  • 入库时间 2022-08-21 11:06:27

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