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PET PET image analysis method for diagnosis of dementia

机译:PET PET图像分析方法诊断痴​​呆

摘要

The present invention relates to a method of analyzing PET (positron emission tomography) for diagnosis of dementia, and more specifically, sagittal plane and coronal view from an axial plane image obtained from a PET image of a axial plane of the brain. After automatically generating a coronal plane image, the artificial intelligence learning results are used for these three cross-section images to automatically classify and analyze normal, early, middle, late or normal, dementia stages for dementia. It relates to a deep learning-based PET image analysis method for diagnosis and prediction of dementia. In the present invention, a plurality of axial plane images are generated by taking a single layer of the axial plane of the brain, and then image interpolation is performed on the plurality of axial plane images to generate a 3D model, and the 3D model Sampling the sagittal and coronal planes at regular intervals to generate a plurality of sagittal and multiple coronal images and performing learning using a machine learning method. A PET image analysis method comprising a reasoner performing a diagnosis of dementia performing a process of inferring a degree, Providing a plurality of predetermined axial plane images; Generating a predetermined sagittal image and a coronal image, respectively, based on the predetermined axial plane image using a 3D model generator; The predetermined axial plane image, the predetermined sagittal plane image, and the predetermined coronal plane image are provided to an axial plane inference machine, a sagittal plane inference machine, and a coronal plane inference machine, and the axial plane inference machine, the sagittal plane inference machine, and And performing a diagnosis of dementia by inputting the results of the coronal inference machine into the selector, Normal, initial, and dementia output values for the axial image , , Define each as Normal, initial, and dementia output values for the sagittal image , , Define each as Normal, initial, and dementia output values for the coronal image , , If each is defined as, The average values of the output values of the axial plane image, the sagittal plane image, and the coronal plane image are calculated as in the following equations (1), (2), (3), (One) (2) (3) Diagnosis result is calculated based on the following formula (4). (4) here, As the final diagnosis result, 0 is normal, 1 is early, and 2 is dementia. max() is characterized by being the maximum value among the elements. When performing the PET image analysis method based on deep learning for diagnosis and prediction of dementia according to the present invention, there is an advantage that more three-dimensional and precise dementia diagnosis is possible compared to the conventional diagnosis method based on only a specific image of the brain.
机译:本发明涉及一种分析PET(正电子发射断层扫描)以诊断痴呆的方法,更具体地,涉及一种根据从脑轴平面的PET图像获得的轴平面图像的矢状面和冠状面的视图。在自动生成冠状平面图像后,将人工智能学习结果用于这三个横截面图像,以自动分类和分析痴呆的正常,早期,中期,晚期或正常痴呆阶段。它涉及基于深度学习的PET图像分析方法,用于痴呆的诊断和预测。在本发明中,通过获取单层的大脑轴向平面来生成多个轴向平面图像,然后对多个轴向平面图像执行图像插值以生成3D模型,并且3D模型采样矢状和冠状平面以规则的间隔产生多个矢状和多个冠状图像,并使用机器学习方法进行学习。一种PET图像分析方法,包括:推理机,进行痴呆的诊断,并进行推断程度的过程;提供多个预定的轴向平面图像;使用3D模型生成器基于预定轴向平面图像分别生成预定矢状图像和冠状图像;预定轴向平面图像,预定矢状平面图像和预定冠状平面图像被提供给轴向平面推断机,矢状平面推断机和冠状平面推断机,以及轴向平面推断机,矢状平面推理机,然后通过将冠状推理机的结果输入到选择器中来执行痴呆的诊断,将轴向图像的正常,初始和痴呆输出值分别定义为正常,初始和痴呆输出值。矢状图像,,分别定义为冠状图像的正常,初始和痴呆的输出值,如果每个定义为轴向平面图像,矢状面图像和冠状平面图像的输出值的平均值按照以下等式(1),(2),(3),(一个)(2)(3)计算诊断结果。根据以下公式(4)计算诊断结果。 (4)在这里,作为最终诊断结果,0正常,1早期,2痴呆。 max()的特征是元素之间的最大值。当根据本发明执行基于深度学习的PET图像分析方法以用于痴呆的诊断和预测时,与仅基于特定图像的常规诊断方法相比,具有更多的三维和精确的痴呆诊断可能性。的大脑。

著录项

  • 公开/公告号KR20200094393A

    专利类型

  • 公开/公告日2020-08-07

    原文格式PDF

  • 申请/专利权人 동아대학교 산학협력단;

    申请/专利号KR20190011813

  • 发明设计人 박장식;강도영;

    申请日2019-01-30

  • 分类号A61B5;A61B6;A61B6/03;

  • 国家 KR

  • 入库时间 2022-08-21 11:06:15

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