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Model for predicting the toxic side effects of the intended drug and method thereof

机译:预测预期药物毒性副作用的模型及其方法

摘要

The present invention comprises the steps of: (a) selecting an RPS6KB1, FAK, or STK35 kinase inhibitor from the target drug corresponding to the kinase inhibitor; (b) measuring the IC50 or% inhibition of the selected inhibitor; And (c) it provides a method for predicting the presence or absence of toxic side effects of the target drug comprising the step of calculating the molecular expression of the inhibitor having the measured value.
机译:本发明包括以下步骤:(a)从对应于激酶抑制剂的靶药物中选择RPS6KB1,FAK或STK35激酶抑制剂; (b)测量所选抑制剂的IC50或抑制百分比;并且(c)提供了预测目标药物的毒性副作用的存在或不存在的方法,该方法包括计算具有测量值的抑制剂的分子表达的步骤。

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