METHOD modeling capabilities toxic effects when used together several drugs

摘要

A method of modeling a possible toxic effect when used together several drugs, including a comprehensive assessment of morphological and physiological disorders observed in fitotestah, characterized in that the tested individually each preparation and their mixture at the recommended dosage, morfofiziologicheskie violations detected on seeds cress (Lepidium sativum), wherein the disorders are indicators morfofiziologicheskih decrease in seed germination, reduction of the average total length of the sprouts and the change in average with uhogo weight seedlings, as well as the nature of dependencies between the length and weight of seedlings after statistical processing results predict a possible toxic effect of mixtures of drugs in the safety assessment of mixtures of biologically active substances.