首页> 外国专利> Wrinkle improvement cosmetic containing ginsenoside Rg3, Rg5 and Rk1

Wrinkle improvement cosmetic containing ginsenoside Rg3, Rg5 and Rk1

机译:包含人参皂苷Rg3,Rg5和Rk1的抗皱改善化妆品

摘要

The present invention relates to a cosmetic composition for improving wrinkles containing ginsenosides Rg3, Rg5, and Rk1, more specifically, containing ginsenosides Rg3, Rg5, and Rk1, wherein the water-soluble Rg3 (S) isomer is fat-soluble Rg3 (R ) It is related to a cosmetic composition that is more effective in improving wrinkles caused by stress stimulation by ultraviolet rays and infrared rays, characterized in that it contains more than isomers. According to the present invention, ginsenosides can be separated and purified by an enzymatic conversion method rather than a normal boiling or boiling method to include three or more times the water-soluble Rg3 (S) isomer than the fat-soluble Rg3 (R) isomer. In addition, the cosmetic composition for improving wrinkles containing ginsenosides Rg3, Rg5, and Rk1 of the present invention inhibits skin aging by inhibiting 11β-HSD1, a stress hormone related to skin aging due to photoaging, and MMP-1, a matrix proteolytic enzyme. It can have a preventive or improvement effect.
机译:本发明涉及用于改善皱纹的化妆品组合物,其包含人参皂苷Rg3,Rg5和Rk1,更具体地,包含人参皂苷Rg3,Rg5和Rk1,其中水溶性Rg3(S)异构体是脂溶性Rg3(R)。本发明涉及一种化妆品组合物,其在改善由紫外线和红外线的应力刺激引起的皱纹方面更有效,其特征在于它含有比异构体更多的化妆品。根据本发明,人参皂苷可以通过酶促转化方法而不是常规沸腾或沸腾方法来分离和纯化,以包含比脂溶性Rg3(R)异构体三倍或更多倍的水溶性Rg3(S)异构体。 。另外,本发明的含有人参皂苷Rg3,Rg5和Rk1的用于改善皱纹的化妆品组合物通过抑制与由于光老化引起的皮肤衰老相关的应激激素11β-HSD1和基质蛋白水解酶MMP-1来抑制皮肤衰老。 。它可以具有预防或改善作用。

著录项

  • 公开/公告号KR102114682B1

    专利类型

  • 公开/公告日2020-05-26

    原文格式PDF

  • 申请/专利权人 코스맥스 주식회사;

    申请/专利号KR20187025044

  • 申请日2017-03-13

  • 分类号A61K8/60;A61K8/02;A61K8/63;A61K8/97;A61Q19/08;

  • 国家 KR

  • 入库时间 2022-08-21 11:04:39

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