首页> 外国专利> DRD2 Biomarker Composition for Diagnosing Colorectal Cancer Specifically Binding to Arginine-methylated Dopamine Receptor D2

DRD2 Biomarker Composition for Diagnosing Colorectal Cancer Specifically Binding to Arginine-methylated Dopamine Receptor D2

机译:用于诊断结直肠癌与精氨酸甲基化的多巴胺受体D2特异性结合的DRD2生物标志物组合物

摘要

The present invention relates to a biomarker composition for diagnosing colorectal cancer and a diagnostic kit for diagnosing colorectal cancer using an expression level of DRD2 (Dopamine Receptor D2) methylated with arginine as an index, and a method for providing information for colorectal cancer diagnosis. By using an antibody that specifically recognizes the diagnostic biomarker arginine methylated DRD2 protein, the expression level of DRD2 methylated arginine in the blood of a suspected cancer patient is measured, so blood can be analyzed easily without biopsy from the patient. , When the expression of DRD2 in which arginine is methylated is lower than that in normal people, it can be diagnosed as colon cancer.
机译:本发明涉及使用精氨酸甲基化的DRD2(多巴胺受体D2)的表达水平作为指标,用于诊断大肠癌的生物标志物组合物和用于诊断大肠癌的诊断试剂盒,以及提供用于大肠癌诊断的信息的方法。通过使用特异性识别诊断性生物标志物精氨酸甲基化DRD2蛋白的抗体,可以测量可疑癌症患者血液中DRD2甲基化精氨酸的表达水平,因此无需患者活检即可轻松分析血液。 ,当精氨酸被甲基化的DRD2的表达低于正常人时,可以诊断为结肠癌。

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