-11 Antimicrobial anti-inflammatory and anti-acne composition containing the Scolopendrasin-11 peptide from Scolopendra subspinipes mutilans as an active component

摘要

The present invention relates to an antimicrobial, antifungal, anti-inflammatory or anti-acne composition comprising the Scolopendracin-11 peptide derived from Scolopendra subspinipes mutilans as an active ingredient. Scolopendracin-11 peptide is excellent in antibacterial or antifungal effect against Staphylococcus epidermidis , Propionibacterium acnes , Candida albicans , etc., Inhibits NO secretion, or IL-6 (interleukin-6), IL-1β (interleukin-1β), iNOS (inducible NO synthase), TNF-α (tumor necrosis factor-α), or COX-2 (cyclo oxygenase-2) It is excellent in controlling various inflammatory reactions, such as inhibiting the expression of, and can be easily used as a composition for antibacterial, antifungal, anti-inflammatory or anti-acne.