RANKL Mutation of RANKL and pharmaceutical composition for preventing or treating osteoporosis comprising the same

摘要

The present invention can inhibit the production of osteoclasts by inducing the generation of anti-RANKL antibodies as antigens in the body, and comprising a mutant of RANKL protein that binds to RANK and does not induce the differentiation of osteoclasts, and an active ingredient thereof. , It relates to the provision of a composition for preventing or treating bone metabolic diseases.