首页> 外国专利> Mutation of RANKL, and pharmaceutical composition for preventing or treating osteoporosis comprising the same

Mutation of RANKL, and pharmaceutical composition for preventing or treating osteoporosis comprising the same

机译:RANKL的突变,以及用于预防或治疗骨质疏松的药物组合物

摘要

The present invention can inhibit the production of osteoclasts by inducing the production of anti-RANKL antibodies as antigens in the body, and binds to RANK, but does not induce differentiation of osteoclasts and contains mutants of RANKL protein and active ingredients thereof , It relates to the provision of a composition for preventing or treating bone metabolic disease.
机译:本发明可以通过诱导体内抗RANKL抗体作为抗原而抑制破骨细胞的产生,并与RANK结合,但不诱导破骨细胞的分化,并且包含RANKL蛋白的突变体及其活性成分,涉及提供用于预防或治疗骨代谢疾病的组合物。

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