Composition for inducing selective apoptosis undifferentiated pluripotent stem cells comprising prunellae spica extracts and the Method for inducing selective apoptosis using the same

摘要

The present invention relates to a composition for inducing selective apoptosis of undifferentiated pluripotent stem cells comprising hagocho serrata extract as an active ingredient, specifically inducing selective apoptosis of undifferentiated pluripotent stem cells comprising hagocho serrata extract as an active ingredient A composition for selective removal of undifferentiated pluripotent stem cells comprising a hagocho serrata extract as an active ingredient, (a) preparing a cell sample including undifferentiated pluripotent stem cells and differentiated cells; And (b) selectively removing undifferentiated pluripotent stem cells by treating the cell sample with hagocho serrata extract; including, a method for removing undifferentiated pluripotent stem cells, and removing undifferentiated pluripotent stem cells by the method It relates to the cell composition. In a situation where the undifferentiated stem cells remaining in the process of differentiation of pluripotent stem cells have a problem in that they can form teratoma (teratoma) when transplanted as a cell therapy agent, the composition containing the hagochochod extract of the present invention is a pluripotent stem cell. Since only the stem cells remaining in the undifferentiated state during the differentiation process can be effectively removed, it can be used to develop a safe stem cell therapeutic agent.