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LACTIC BACTERIA AND THEIR APPLICATION FOR TREATMENT FOR THE PURPOSE OF PREVENTION, INHIBITING AND / OR REDUCING THE FORMATION OF BACTERIAL BIOFILMS

机译:乳酸菌及其在预防,抑制和/或减少细菌生物膜形成中的应用

摘要

The present invention relates to selected bacterial strains belonging to the genus Lactobacillus and the use thereof for the treatment of bacterial biofilms and, specifically, for preventive treatment aimed at inhibiting and/or reducing the formation of bacterial biofilms. In particular, the present invention relates to the following bacterial strains belonging to the genus Lactobacillus selected from the group comprising or, alternatively, consisting of Lactobacillus plantarum LMC1 (DSM 32252), Lactobacillus reuteri LMC3 (DSM 32253), Lactobacillus paracasei LMC4 (DSM 32254), Lactobacillus reuteri LMC5 (DSM 32255), Lactobacillus rhamnosus LMC6 (DSM 32256), Lactobacillus rhamnosus LMC7 (DSM 32257), Lactobacillus paracasei LMC8 (DSM 32258), Lactobacillus reuteri LMC9 (DSM 32259) and Lactobacillus rhamnosus LMC10 (DSM 32260) and the use thereof for the treatment of bacterial biofilms and, specifically, for preventive treatment aimed at inhibiting and/or reducing the formation of bacterial biofilms. Furthermore, the present invention relates to a pharmaceutical composition, a composition for a medical device or a composition for dietary supplements comprising a mixture which comprises or, alternatively, consists of one or more of the bacterial strains specified above and, optionally, pharmaceutical or food grade technological additives and/or excipients, for the treatment of bacterial biofilms and, specifically, for preventive treatment aimed at inhibiting and/or reducing the formation of bacterial biofilms.
机译:本发明涉及属于乳杆菌属的选择的细菌菌株及其在治疗细菌生物膜中的用途,特别是在旨在抑制和/或减少细菌生物膜形成的预防性治疗中的用途。特别地,本发明涉及以下乳杆菌属的细菌菌株,其选自植物乳杆菌LMC1(DSM 32252),路氏乳杆菌LMC3(DSM 32253),副干酪乳杆菌LMC4(DSM 32254) ),罗伊氏乳杆菌LMC5(DSM 32255),鼠李糖乳杆菌LMC6(DSM 32256),鼠李糖乳杆菌LMC7(DSM 32257),副干酪乳杆菌LMC8(DSM 32258),罗伊氏乳杆菌LMC9 LMS9(DSM 32259)和罗氏乳杆菌LMC9(DSM 32259)和其在治疗细菌生物膜中的用途,特别是在旨在抑制和/或减少细菌生物膜形成的预防性治疗中的用途。此外,本发明涉及药物组合物,用于医疗器械的组合物或用于膳食补充剂的组合物,其包含混合物,所述混合物包含或可选地由一种或多种上述细菌菌株以及任选的药物或食品组成级别的技术添加剂和/或赋形剂,用于细菌生物膜的治疗,尤其是用于旨在抑制和/或减少细菌生物膜形成的预防性治疗。

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