METHOD OF PRODUCING A PREPARATION OF A RIBONUCLEOPROTEIN COMPLEX OF CRISPR / CAS AND A PREPARATION FOR DETECTING PROVIRAL DNA OF HUMAN IMMUNODEFICIENCY VIRUS INTEGRATED INTO A HUMAN GENOME IN ULTRA-LOW CONCENTRATIONS

摘要

FIELD: biotechnology.;SUBSTANCE: invention relates to biotechnology, specifically to preparing a CRISPR / CAS ribonucleoprotein preparation, and can be used to detect proviral DNA of human immunodeficiency virus (HIV-1).;EFFECT: invention provides detecting single copies of proviral DNA of HIV-1 integrated into the human genome.;6 cl, 11 dwg, 4 tbl, 5 ex