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METHOD OF PREPARING ULTRATHIN TRANSPLANTS FOR POSTERIOR LAYER KERATOPLASTY

机译:一种用于后层角膜塑形的超薄移植物的制备方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, specifically to ophthalmology. To form an ultrathin corneal graft for posterior layer-by-layer keratoplasty, transplant thickness is measured by optical coherence tomography (OCT), a section of the thickness of the donor cornea with microkeratome, repeated OCT pachymetry and exposure to an excimer laser. Cut of thickness of the donor cornea is made with microkeratome MoriaSLK2 or MoriaSLK3 with a turbine of longitudinal type head of caliber 450, 500 or 550 microns. It is followed by repeated OCT pachymetry to obtain a detailed map of thickness of excess corneal layers of the donor. Data are entered into the program of the excimer laser Microscan 500 or Microscan 1000 "Complex FTK" and act at wavelength 193 nm, pulse repetition frequency of 500 or 1,000 Hz, respectively, diameter of laser spot 0.9 mm, maximum diameter of ablation 10.9 mm. Transplant excess thickness is simultaneously evaporated in the central and peripheral regions so that the peripheral part evaporates in a greater volume than the central one, which results in a uniform transplant formation.;EFFECT: method enables preparing an ultrathin graft with no risk of rejection of the donor material with a planned thickness, wherein the adhesion of the donor material to the cornea of the recipient is improved and a hypermetropic shift is reduced, which increases visual acuity.;1 cl, 3 ex
机译:技术领域本发明涉及医学,尤其涉及眼科。为了形成用于后层角膜移植的超薄角膜移植物,可通过光学相干断层扫描(OCT),供体角膜厚度的一部分和微角膜刀,重复的OCT测厚法以及暴露于准分子激光来测量移植物的厚度。用具有250、500或550微米口径的纵向型头部的涡轮的微型角膜刀MoriaSLK2或MoriaSLK3切割供体角膜的厚度。随后进行重复的OCT测厚法,以获得供体多余角膜层厚度的详细图。将数据输入到准分子激光器Microscan 500或Microscan 1000“ Complex FTK”的程序中,并分别作用于波长193 nm,脉冲重复频率500或1,000 Hz,激光光斑直径0.9 mm,最大消融直径10.9 mm 。移植物多余的厚度同时在中央和周围区域蒸发,从而使周围部分的蒸发量大于中央部分,从而形成均匀的移植物。效果:该方法能够制备超薄移植物,而没有排斥移植物的风险。供体材料具有计划的厚度,其中供体材料与受体角膜的粘附性得到改善,远视眼移位减少,从而增加了视力。; 1 cl,3 ex

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