Recombinant microorganism, process for its production and its use in the production of coenzyme Q10

摘要

The present disclosure relates to a recombinant microorganism, a process for its production and its use in the production of coenzyme Q10. In particular, the present disclosure provides a method of exogenous introduction of a gene encoding the global regulatory protein irrE in order to construct a recombinant microorganism. This recombinant microorganism is suitable for the production of coenzyme Q10 by fermentation processes and is particularly suitable for the production of oxidized coenzyme Q10. The recombinant microorganism of the present disclosure is stress resistant and has a good tolerance to harsh environmental conditions including high osmotic pressure and high redox potential, which makes it possible to significantly increase the yield of coenzyme Q10, in particular the yield of oxidized coenzyme Q10.