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Process for the fermentative production of oxidized coenzyme Q10 as well as high-content oxidized coenzyme Q10 produced from it

机译:发酵生产氧化型辅酶Q10的方法以及由其生产的高含量氧化型辅酶Q10的方法

摘要

The present application relates to a method for the fermentative production of oxidized coenzyme Q10 and high-content oxidized coenzyme Q10 produced therefrom. For the process for the fermentative production of oxidized coenzyme Q10, the oxidation-reduction potential (ORP) of a fermentation broth is regulated to -50 to 300 Mv in a fermentation process of a production strain, and the oxidation-reduction potential (ORP) of the fermentation broth is preferably increased 50 to 200 mV regulated. By regulating the ORP of the fermentation broth, the method for fermentative production of oxidized coenzyme Q10 enables the proportion of oxidized coenzyme Q10 in the coenzyme Q10 produced by microorganisms to reach 96% or more, and the product is essentially composed of a single one Component together, which makes post-treatment more convenient. Oxidized coenzyme Q10 is more stable than reduced coenzyme Q10, and compared to coenzyme Q10, which is obtained with fermentation processes from the prior art, high-content oxidized coenzyme Q10 breaks down in organisms to a lesser extent. In addition, the fermentation process of the present application is highly effective.
机译:本发明涉及发酵生产氧化型辅酶Q10的方法和由其生产的高含量氧化型辅酶Q10。对于发酵生产氧化型辅酶Q10的方法,在生产菌株的发酵过程中将发酵液的氧化还原电位(ORP)调节至-50至300Mv,并且氧化还原电位(ORP)优选将发酵液的pH调节为50-200mV。通过调节发酵液的ORP,通过发酵生产氧化型辅酶Q10的方法,使微生物产生的辅酶Q10中的氧化型辅酶Q10的比例达到96%以上,并且该产物基本上由单一一种组分组成。在一起,使后处理更加方便。氧化型辅酶Q10比还原型辅酶Q10更稳定,并且与通过现有技术发酵工艺获得的辅酶Q10相比,高含量的氧化型辅酶Q10在生物体中的分解程度较小。另外,本申请的发酵方法是高度有效的。

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