DISPOSITIFS ET PROCÉDÉS D'AMÉLIORATION DE L'IMMUNOGÉNICITÉ VIS-À-VIS D'UNE VACCINATION INTRADERMIQUE

摘要

Devices and methods that utilize an occlusive dressing in combination with a topical pharmaceutical agent to enhance vaccine efficacy are described. The occlusive dressing delivers a defined dose of a topical pharmaceutical agent that enhances immune system reactivity to a vaccine to the site of vaccination, and provides a barrier that maintains a layer of the topical pharmaceutical agent on the skin for a desired period to time while also providing a port through which an immunizing composition can be administered. In some embodiments the occlusive dressing includes a wound dressing for covering the injection site following vaccination.