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治疗或预防RAS-介导的疾病的方法

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摘要

本发明公开了化合物，例如式I化合物，其中R、R₀、R₁‑R₈、n、X、Y、Y'和E如本文所述，含有这些化合物的药物组合物，以及治疗或预防由ras基因介导的疾病或病症例如癌症的方法

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公开/公告号CN107466232B

专利类型发明专利
公开/公告日2021-06-29

原文格式PDF
申请/专利权人 ADT制药有限责任公司;
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申请/专利号CN201580076204.6
发明设计人 G.A.皮亚扎;X.陈;A.B.基顿;M.R.博伊德;
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申请日2015-12-16
分类号A61K31/165(20060101);A61K31/167(20060101);A61K31/216(20060101);A61K31/341(20060101);A61K31/40(20060101);A61K31/401(20060101);A61K31/421(20060101);A61K31/4402(20060101);A61K31/4406(20060101);A61K31/496(20060101);A61K31/5375(20060101);A61K31/5377(20060101);A61K45/06(20060101);C07C235/34(20060101);C07C311/29(20060101);C07D207/14(20060101);C07D207/335(20060101);C07D213/40(20060101);C07D213/75(20060101);C07D307/52(20060101);G01N33/574(20060101);A61P35/00(20060101);
代理机构11105 北京市柳沈律师事务所;
代理人曹立莉
地址美国阿拉巴马州
入库时间 2022-08-23 12:03:25

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1. 治疗或预防RAS-介导的疾病的方法 [P] . 中国专利： CN107466232B . 2021.06.29
2. 治疗或预防免疫介导的疾病的方法以及用于该方法中的药物组合物 [P] . 中国专利： CN1691947A . 2005-11-02
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