In this thesis, we use a semidefinite relaxation based branch-and-bound method to solve nonconvex quadratic programming problems. Firstly, we show an interval branch-and-bound method to calculate the bounds for the minimum of bounded polynomials. Then we demonstrate four SDP relaxation methods to solve nonconvex Box constrained Quadratic Programming (BoxQP) problems and the comparison of the four methods. For some lower dimensional problems, SDP relaxation methods can achieve tight bounds for the BoxQP problem; whereas for higher dimensional cases (more than 20 dimensions), the bounds achieved by the four Semidefinite programming (SDP) relaxation methods are always loose. To achieve tight bounds for higher dimensional BoxQP problems, we combine the branch-and-bound method and SDP relaxation method to develop an SDP relaxation based branch-and-bound (SDPBB) method. We introduce a sensitivity analysis method for the branching process of SDPBB. This sensitivity analysis method can improve the convergence speed significantly.
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