首页> 外文OA文献 >PROOF OF CONCEPT DESIGN FOR A REMOTELY POWERED DEEP BRAIN STIMULATION DEVICE
【2h】

PROOF OF CONCEPT DESIGN FOR A REMOTELY POWERED DEEP BRAIN STIMULATION DEVICE

机译:远程深脑刺激装置概念设计的证明

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Parkinson's disease is a neurodegenerative disorder that causes tremor, stiffness, and slowness of movement. The first line of treatment for the disease is the administration of drugs. Over a period of time, these drugs slowly lose their affect to arrest the symptoms associated with Parkinson's disease. Once a patient becomes refractory to drug treatment, one alternative treatment option is Deep Brain Stimulation (DBS). In DBS, a probe is implanted in the basal ganglia area of the brain to administer electric pulses that curb the aforementioned symptoms. Although not fully understood, DBS is becoming a more widely accepted treatment, with various implantable devices currently on the market. These devices, however, require the implantation of a relatively large battery and control pack in the chest with subcutaneous wires threaded up through the neck to the top of the skull. The control pack and wires are a common source of irritation and infection, sometimes necessitating long periods of antibiotics or even removal of the device. Furthermore, the device is susceptible to magnetic interference and has a limited battery life. After the average 3- to 5-year lifespan of an implant's battery, another surgery is required to replace the device. The aim of this research is to design a small remotely powered device capable of driving a DBS probe from directly under the scalp. Successful development and proof of viability will form a basis for the conceptual redesign of currently marketed devices in order to eliminate the intrusive battery pack and wires, as well as the health risks commonly associated with them and the implantation procedure.
机译:帕金森氏病是一种神经退行性疾病,会引起震颤,僵硬和运动缓慢。该疾病的第一线治疗是药物管理。在一段时间内,这些药物会慢慢失去作用,以阻止与帕金森氏病相关的症状。一旦患者无法接受药物治疗,另一种治疗选择是深部脑刺激(DBS)。在DBS中,将探针植入大脑的基底神经节区域,以施加电脉冲以抑制上述症状。尽管尚未完全了解,但DBS正在成为一种更广泛接受的治疗方法,目前市场上有各种可植入设备。但是,这些装置需要在胸部植入较大的电池和控制包,并且皮下的金属丝穿过脖子穿过,到达头骨的顶部。控制包和电线是常见的刺激和感染源,有时需要长期使用抗生素,甚至需要拆除设备。此外,该设备容易受到电磁干扰,并且电池寿命有限。植入物电池的平均使用寿命为3至5年后,需要再次进行手术以更换该设备。这项研究的目的是设计一种小型的远程供电设备,该设备能够从头皮正下方驱动DBS探头。成功的开发和可行性证明将成为当前市场上设备重新概念设计的基础,以消除侵入性的电池组和电线以及通常与之相关的健康风险和植入程序。

著录项

  • 作者

    Hackworth Steven A;

  • 作者单位
  • 年度 2005
  • 总页数
  • 原文格式 PDF
  • 正文语种 en
  • 中图分类

相似文献

  • 外文文献
  • 中文文献
  • 专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号