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STUDIES ON ACID-BASE BALANCE IN MAINTENANCE HEMODIALYSIS PART1. CHANGES OF ACID-BASE BALANCE IN THE COURSE OF HEMODIALYSIS

机译:维持性血液透析中酸碱平衡的研究第1部分。血液透析过程中酸碱平衡的变化

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摘要

Acid-base balance was studied before, during and after hemodialysis on four patients on the maintenance hemodialysis with the Kiil type artificial kidney. The patients were divided into two groups, Group I (one 8 hours dialysis per week) and Group II (two 8 hours dialysis per week), according to their 24 hour urinary volume. 1) Blood pH: Both Group I and II showed some alkalemia at the end of hemodialysis, Group II being more remarkable than Group I. Comparison of blood pH of the inflow and outflow side did not show difference. After hemodialysis pH gradually decreased but remained within normal range even 12 to 48 hours. 2) PCO2: During hemodialysis it showed very little change. After hemodialysis, it gradually increased and reached the highest value in 6 hours followed by gradual decrease. Hypocapnia was striking on the outflow side compared with the inflow side. 3) Actual bicarbonate returned to the normal value at the end of hemodialysis, but somewhat slowly in Group II. Hypobasemia was remarkable on the outflow side. 4) Base excess was corrected at the end of hemodialysis both Group I and II. After dialysis, it gradually decreased just as actual bicarbonate did. Hypobasemia was still striking on the outflow side. 5) Hemodialysis using dialysate containing 33 mEq/L of acetate did not result in the sufficient improvement of acid-base balance in some cases. This fact suggests composition of dialysate has to be changed by case for the better acid-base balance.
机译:在四例使用Kiil型人工肾脏维持血液透析的患者进行血液透析之前,期间和之后,研究了酸碱平衡。根据患者的24小时尿液量将其分为两组:I组(每周一次8小时透析)和II组(每周两次8小时透析)。 1)血液pH值:I组和II组在血液透析结束时均显示出一些碱血症,II组比I组更显着。流入侧和流出侧的血液pH值比较没有差异。血液透析后,pH逐渐降低,但即使在12至48小时内也保持在正常范围内。 2)PCO2:血液透析期间几乎没有变化。血液透析后,它逐渐升高并在6小时内达到最高值,然后逐渐降低。与流入侧相比,低碳酸血症发作在流出侧。 3)血液透析结束时,实际的碳酸氢盐恢复到正常值,但在第II组中有些缓慢。低血钠在流出侧很明显。 4)在第I组和第II组血液透析结束时纠正基础过量。透析后,它逐渐减少,就像实际的碳酸氢盐一样。低血钠症仍然在流出方面令人震惊。 5)在某些情况下,使用含33 mEq / L乙酸盐的透析液进行血液透析不能充分改善酸碱平衡。这个事实表明,为了更好的酸碱平衡,必须根据情况改变透析液的组成。

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    田戸 治;

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  • 年度 1972
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  • 原文格式 PDF
  • 正文语种 ja
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