Fast, accurate photon beam accelerator modeling using BEAMnrc : A systematic investigation of efficiency enhancing methods and cross-section data

摘要

In this work, an investigation of efficiency enhancing methods and cross-section data in the BEAMnrc Monte Carlo (MC) code system is presented. Additionally, BEAMnrc was compared with VMC++, another special-purpose MC code system that has recently been enhanced for the simulation of the entire treatment head. BEAMnrc and VMC++ were used to simulate a 6\u2002MV photon beam from a Siemens Primus linear accelerator (linac) and phase space (PHSP) files were generated at 100\u2002cm source-to-surface distance for the 10\ud710 and 40\ud740\u2002cm2 field sizes. The BEAMnrc parameters/techniques under investigation were grouped by (i) photon and bremsstrahlung cross sections, (ii) approximate efficiency improving techniques (AEITs), (iii) variance reduction techniques (VRTs), and (iv) a VRT (bremsstrahlung photon splitting) in combination with an AEIT (charged particle range rejection). The BEAMnrc PHSP file obtained without the efficiency enhancing techniques under study or, when not possible, with their default values (e.g., EXACT algorithm for the boundary crossing algorithm) and with the default cross-section data (PEGS4 and Bethe\u2013Heitler) was used as the \u201cbase line\u201d for accuracy verification of the PHSP files generated from the different groups described previously. Subsequently, a selection of the PHSP files was used as input for DOSXYZnrc-based water phantom dose calculations, which were verified against measurements. The performance of the different VRTs and AEITs available in BEAMnrc and of VMC++ was specified by the relative efficiency, i.e., by the efficiency of the MC simulation relative to that of the BEAMnrc base-line calculation. The highest relative efficiencies were \u223c935 (\u223c111\u2002min on a single 2.6\u2002GHz processor) and \u223c200 (\u223c45\u2002min on a single processor) for the 10\ud710 field size with 50 million histories and 40\ud740\u2002cm2 field size with 100 million histories, respectively, using the VRT directional bremsstrahlung splitting (DBS) with no electron splitting. When DBS was used with electron splitting and combined with augmented charged particle range rejection, a technique recently introduced in BEAMnrc, relative efficiencies were \u223c420 (\u223c253\u2002min on a single processor) and \u223c175 (\u223c58\u2002min on a single processor) for the 10\ud710 and 40\ud740\u2002cm2 field sizes, respectively. Calculations of the Siemens Primus treatment head with VMC++ produced relative efficiencies of \u223c1400 (\u223c6\u2002min on a single processor) and \u223c60 (\u223c4\u2002min on a single processor) for the 10\ud710 and 40\ud740\u2002cm2 field sizes, respectively. BEAMnrc PHSP calculations with DBS alone or DBS in combination with charged particle range rejection were more efficient than the other efficiency enhancing techniques used. Using VMC++, accurate simulations of the entire linac treatment head were performed within minutes on a single processor. Noteworthy differences (\ub11%\u20133%) in the mean energy, planar fluence, and angular and spectral distributions were observed with the NIST bremsstrahlung cross sections compared with those of Bethe\u2013Heitler (BEAMnrc default bremsstrahlung cross section). However, MC calculated dose distributions in water phantoms (using combinations of VRTs/AEITs and cross-section data) agreed within 2% of measurements. Furthermore, MC calculated dose distributions in a simulated water/air/water phantom, using NIST cross sections, were within 2% agreement with the BEAMnrc Bethe\u2013Heitler default case.