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Evaluating the drivers of and obstacles to the willingness to use cognitive enhancement drugs: the influence of drug characteristics, social environment, and personal characteristics

机译:评估使用认知增强药物意愿的驱动因素和障碍:药物特性,社会环境和个人特性的影响

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摘要

BackgroundThe use of cognitive enhancement (CE) by means of pharmaceutical agents has been the subject of intense debate both among scientists and in the media. This study investigates several drivers of and obstacles to the willingness to use prescription drugs non-medically for augmenting brain capacity.MethodsWe conducted a web-based study among 2,877 students from randomly selected disciplines at German universities. Using a factorial survey, respondents expressed their willingness to take various hypothetical CE-drugs; the drugs were described by five experimentally varied characteristics and the social environment by three varied characteristics. Personal characteristics and demographic controls were also measured.ResultsWe found that 65.3% of the respondents staunchly refused to use CE-drugs. The results of a multivariate negative binomial regression indicated that respondents’ willingness to use CE-drugs increased if the potential drugs promised a significant augmentation of mental capacity and a high probability of achieving this augmentation. Willingness decreased when there was a high probability of side effects and a high price. Prevalent CE-drug use among peers increased willingness, whereas a social environment that strongly disapproved of these drugs decreased it. Regarding the respondents’ characteristics, pronounced academic procrastination, high cognitive test anxiety, low intrinsic motivation, low internalization of social norms against CE-drug use, and past experiences with CE-drugs increased willingness. The potential severity of side effects, social recommendations about using CE-drugs, risk preferences, and competencies had no measured effects upon willingness.ConclusionsThese findings contribute to understanding factors that influence the willingness to use CE-drugs. They support the assumption of instrumental drug use and may contribute to the development of prevention, policy, and educational strategies.
机译:背景技术通过药剂的认知增强(CE)的使用一直是科学家和媒体之间激烈辩论的主题。这项研究调查了非医学目的使用处方药来增强脑容量的几种驱动因素和障碍。方法我们对来自德国大学随机选择学科的2877名学生进行了基于网络的研究。通过析因调查,受访者表示愿意服用各种假想的CE药品;通过五个实验变化的特征来描述毒品,通过三个变化特征来描述社会环境。结果还发现,有65.3%的受访者坚决拒绝使用CE药物。多变量负二项式回归的结果表明,如果潜在的药物承诺显着增强心理能力并极有可能实现这种增强,那么受访者使用CE药物的意愿就会增加。当出现副作用的可能性高且价格高时,意愿降低。在同龄人中普遍使用CE药物会增加他们的意愿,而强烈反对这些药物的社会环境会降低这种意愿。关于受访者的特征,明显的学术拖延,较高的认知测试焦虑,较低的内在动机,对使用CE药物的社会规范的内化程度低以及过去使用CE药物的经验增加了人们的意愿。副作用的潜在严重性,关于使用CE药物的社会建议,风险偏好和能力对意愿没有可衡量的影响。结论这些发现有助于理解影响使用CE药物意愿的因素。它们支持使用工具性药物的假设,并可能有助于预防,政策和教育策略的发展。

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