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Paired-angle-rotation scanning optical coherence tomography forward-imaging probe

机译:配对角旋转扫描光学相干断层扫描正像探头

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摘要

We report a novel forward-imaging optical coherence tomography (OCT), needle-probe paired-angle-rotation scanning OCT (PARS-OCT) probe. The probe uses two rotating angled gradient-index lenses to scan the output OCT probe beam over a wide angular arc (∼19° half-angle) of the region forward of the probe. Among other advantages, this probe design is readily amenable to miniaturization and is capable of a variety of scan modes, including volumetric scans. To demonstrate the advantages of the probe design, we have constructed a prototype probe with an outer diameter of 1.65 mm and employed it to acquire four OCT images, with a 45° angle between adjacent images, of the gill structure of a Xenopus laevis tadpole. The system sensitivity was measured to be 93 dB by using the prototype probe with an illumination power of 450 μW on the sample. Moreover, the axial and the lateral resolutions of the probe are 9.3 and 10.3-12.5 μm, respectively.
机译:我们报告了一种新颖的前向成像光学相干断层扫描(OCT),针头探针对角旋转扫描OCT(PARS-OCT)探针。探头使用两个旋转的倾斜梯度折射率透镜在探头前方区域的广角弧(约19°半角)上扫描输出的OCT探头光束。除其他优点外,这种探头设计易于小型化,并能够采用多种扫描模式,包括体积扫描。为了证明探针设计的优势,我们构建了一个外径为1.65 mm的原型探针,并使用它来获取四个非洲爪蟾g结构的OCT图像,相邻图像之间的夹角为45°。通过使用原型探针在样品上施加450μW的照明功率,系统灵敏度测得为93 dB。此外,探头的轴向和横向分辨率分别为9.3和10.3-12.5μm。

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