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Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer

机译：增加的Smad3和Smad2水平降低，通过TMepai / PMepa1在三重阴性乳腺癌中介导TGF-β的功能切换到生长和转移启动子

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Prajjal K. Singha; Srilakshmi Pandeswara; Hui Geng; Rongpei Lan; Manjeri A. Venkatachalam; Albert Dobi; Shiv Srivastava; Pothana Saikumar;
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1. TMEPAI/PMEPA1 inhibits Wnt signaling by regulating beta-catenin stability and nuclear accumulation in triple negative breast cancer cells [J] . Amalia Riezki, Abdelaziz Mohammed, Puteri Meidi Utami, Cellular Signalling . 2019,第期

机译：TMEPAI / PMEPA1通过调节三粘蛋白稳定性和三重阴性乳腺癌细胞中的核积累来抑制WNT信号传导
2. Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer. [J] . Singha PK, Yeh IT, Venkatachalam MA, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2010,第15期

机译：转化生长因子-β（TGF-β）诱导型基因TMEPAI将TGF-β从乳腺癌的抑癌基因转变为肿瘤启动子。
3. Inhibition of CDK-mediated Smad3 phosphorylation reduces the Pin1-Smad3 interaction and aggressiveness of triple negative breast cancer cells [J] . Thomas Alexandra L., Lind Hanne, Hong Angela, Cell cycle . 2017,第15期

机译：CDK介导的SMAD3磷酸化的抑制减少了三重阴性乳腺癌细胞的PIN1-SMAD3相互作用和侵蚀性
4. Functional proteomics reveals a novel regulator of breast cancer growth and metastasis [C] . Miao Liu, Mohammad-Saeid Jami, Xin Huang, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：功能性蛋白质组学揭示了一种新型乳腺癌生长和转移的调节因素
5. Nuclear Basic Fibroblast Growth Factor Regulation of Triple-Negative Breast Cancer Dormancy/Recurrence. [D] . Li, Shenduo. 2014

机译：三阴性乳腺癌休眠/复发的核碱性成纤维细胞生长因子调节。
6. Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer [O] . Prajjal K. Singha, Srilakshmi Pandeswara, Hui Geng, 2019

机译：在三阴性乳腺癌中增加的Smad3和降低的Smad2水平通过TMEPAI / PMEPA1介导了TGF-β从生长抑制物向生长和转移促进子的功能转换。
7. Transforming Growth Factor-β (TGF-β)–Inducible Gene TMEPAI Converts TGF-β from a Tumor Suppressor to a Tumor Promoter in Breast Cancer [O] . Prajjal K. Singha, I-Tien Yeh, Manjeri A. Venkatachalam, 2010

机译：转化生长因子-β（TGF-β） - 剩余基因TMepai将TGF-β转化为肿瘤抑制剂的TGF-β在乳腺癌中的肿瘤启动子

Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer

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