首页> 外文OA文献 >Association Between Pulse Pressure and Carotid Intima-Media Thickness Among Low-Income Adults Aged 45 Years and Older: A Population-Based Cross-Sectional Study in Rural China
【2h】

Association Between Pulse Pressure and Carotid Intima-Media Thickness Among Low-Income Adults Aged 45 Years and Older: A Population-Based Cross-Sectional Study in Rural China

机译:45岁及以上的低收入成年人之间的脉冲压力和颈动脉内膜内膜厚度的关联:中国农村基于人口的横截面研究

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Worldwide, the stroke burden remains severe, especially for people in low socioeconomic groups. Atherosclerosis is a leading cause of stroke that is attracting increasingly greater attention. Blood pressure, including pulse pressure (PP) and systolic (SBP) and diastolic (DBP) blood pressures, is a traditional risk factor for atherosclerosis; its association with carotid intima-media thickness (CIMT) has also been widely studied. However, published studies have not reported on the relationship between PP and CIMT in low-income adults. Thus, this study investigated the relationship between PP and CIMT in a low-income population, in China. A total of 3,789 people, aged ≥45 years and without histories of stroke or cardiovascular disease, were recruited into this study. B-mode ultrasonography was performed to determine CIMTs. Demographic characteristics, physical examination data, previous medical histories, and laboratory test results were collected for each study participant. Multiple linear regression models were used to analyze the association between CIMT and PP. The mean CIMT was 567.1 μm (males, 583.5 μm; females, 555.7 μm). The SBP, DBP, PP, and mean arterial pressure (MAP) values were all positively correlated with CIMT, in the univariate analysis; PP and MAP showed the strongest correlations. In addition, in three multiple linear regression models, PP was shown to be significantly associated with CIMT; each 1-mm Hg increase in PP resulted in a CIMT increase of ≥0.41 μm (all P < 0.001). Our results demonstrated that, when compared with SBP, DBP, and MAP, PP may be the best predictor of CIMT. Thus, controlling blood pressure, especially PP levels, is vital to decreasing the prevalence of atherosclerosis, especially in this low socioeconomic status population in China.
机译:在全球范围内,卒中负担仍然严重,特别是对于低社会经济群体的人。动脉粥样硬化是中风的主要原因,吸引着越来越大的关注。血压,包括脉冲压力(PP)和收缩压(SBP)和舒张(DBP)血压,是动脉粥样硬化的传统风险因素;其与颈动脉内膜介质厚度(CIMT)的关联也得到了广泛研究。然而,公布的研究尚未报告低收入成年人的PP和CIMT之间的关系。因此,本研究调查了中国低收入人群PP与CIMT之间的关系。招募了3,789人,≥45岁,没有中风或心血管疾病的历史,进入这项研究。进行B模式超声检查以确定SIMTS。为每位研究参与者收集人口特征,体检数据,先前的医疗历史和实验室测试结果。使用多元线性回归模型来分析CIMT和PP之间的关联。平均CIMT为567.1μm(雄性,583.5μm;女性,555.7μm)。在单变量分析中,SBP,DBP,PP和平均动脉压(MAP)值与CIMT呈正相关; PP和地图显示了最强的相关性。此外,在三种多元线性回归模型中,PP被证明与CIMT显着相关; PP的每1mm Hg增加导致CIMT增加≥0.41μm(所有P <0.001)。我们的结果表明,与SBP,DBP和地图相比,PP可能是CIMT的最佳预测因子。因此,控制血压,尤其是PP水平,对降低动脉粥样硬化的患病率至关重要,特别是在中国的这种低位社会经济地位。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号