Final Study Report on the Developmental Toxicity Evaluation for Goldenseal ('Hydrastis canadensis') Root Powder Administered in the Feed to Swiss (CD-1 (Trade Name)) Mice on Gestational Days 6 to 17

摘要

Goldenseal (Hydrastis canadensis) root powder is readily available in over-the-counter (OTC) dietary supplements. Thus, the potential hazards of oral exposure during pregnancy warranted further investigation. The present study was designed to evaluate potential developmental toxicity in timed-mated mice exposed to goldenseal root powder in the diet throughout the embryo/fetal period.