Condensation of Anhydrides or Dicarboxylic Acids with Compounds Containing Active Methylene Groups. Part 19: Condensation of Phthalic and Substituted Phthalic Anhydrides with Benzoylacetic Ester

摘要

Phthalylbenzoylacetic ester and its nitro and halogen derivatives were prepared through condensation of phthalic anhydride, nitrophthalic anhydride, and phthalic halide anhydride with benzoylacetic ester in a solution of acetic anhydride and triethylamine. The condensation of hemipinic acid anhydride proceeds similarly, but under more drastic conditions. Derivatives of indan-1,3-dione are also formed, with a small yield, in the reaction of nitrophthalic anhydrides with benzoylacetic ester in the presence of increased quantities of triethylamine.