Biocompatible and Biomimetic Self-Assembly of Functional.

摘要

Understand cell-directed assembly and use it to direct the formation of new bio/nano interfaces and unique cellular behaviors -Investigated the inclusion of multiple amphipathic components to control and tailor interfacial structures and functions -Created new interfaces by incorporating non-native functional proteins to yield new functionalities Extend cell-directed assembly to immobilize various cell types -Encapsulated several new cell lines, including mammalian cells, in nano-structured hosts; investigated the evolving nano-structure and bio/nano interface with grazing incidence small angle x-ray scattering along with epifluoresecence and confocal scanning laster -Used properties of nano-structure to incorporate nutrients and growth vital to different cell types in order to extend cell assembly.