Influencing upon Mammalian Radioresistance with Biologically Active Drug Respistim Plus.

摘要

Radiobiology is a medical knowledge, which studies ionizing radiation and its influence over the human body. Military radiobiology investigates care to soldiers and civil population after radiation exposure. Acute radiation syndrome and its treatment are the main topics of military radiobiology research. These are the three main trends in Bulgarian military radiobiology: Keeping under control the first reaction after acute radiation exposure; Searching and investigating de novo synthesized chemical materials; Stem cells investigation and its clinical applications. Over the past years different biological substances are applied with success. Protection of the hematopoietic and immune systems is a critical area for restoring organism after irradiation. Some radioprotective characteristics of biologically substances, vitamins and essential elements are established. Aim of the study: To determine radioprotective effect of Bulgarian drug Respistim plus -- a mixture of lyophilized bacterial strains in combination with vitamins and essential elements on the proliferation and migration of hematopoietic stem cells, levels of white blood cells and increased 30 days survival after irradiation.