Analytical and Characterization Studies of Organic Chemicals, Drugs, and Drug Formulations for Walter Reed Army Institute of Research, Silver Spring, MD

摘要

During the period October 22, 2008 to October 21, 2009, the project personnel continued to perform chemical/physical analyses on bulk pharmaceutical substances and formulated drug products, and to manufacture dosage formulations of interest to the USAMRMC Drug Development Program for parasitic and infectious diseases, chemical and biological defense, etc. Specific objectives were to design, develop, validate, and apply methods to determine chemical and physical characteristics of the bulk drugs, drug products, to determine their stability under defined conditions, and to seek/work with subcontractors to produce an intravenous dosage form of artesunate.