Histochemical Studies of Skin Burns, Contact and Flash Lamp Burns

摘要

Histochemical studies to evaluate the effects on enzyme activity as a possible cause of cell damage in thermal injury were made on the skin of white rats after contact with a copper block at 60C for 5 seconds and after exposure to thermal radiation of 3.7 calories/sq. cm. from a xenon flash lamp pulse peaking 0.5 milliseconds. The hot copper contact burn caused deep burn lesions with vascular thrombosis. There was no loss of enzyme activity until 4 hours after the burn exposure. The flash lamp exposure showed only shallow tissue damage after 24 hours. There was immediate loss of enzyme activity in the surface epithelium with rapid cell death. (Author)