Evaluation of Short-Term Bioassays to Predict Functional Impairment. Development of Pulmonary Bioassays in Small Animals/Directory of Institutions/Individuals Involved in Utilization

摘要

Mitre has been requested by the U.S. Army Medical Bioengineering Research and Development Laboratory to identify and evaluate short-term bioassays which have demonstrated ability to evaluate and predict pulmonary impairment resulting from toxicant exposures. This directory is a companion to Selected Short-Term Pulmonary Bioassays, MTR-80W00233, which describes available pulmonary testing protocols and assesses their suitability for a screening program. This directory catalogues the organizations currently engaged in pulmonary bioassay utilization or development and provides information concerning specific measurements performed, test systems employed, compounds tested, requirements for anesthesia and terminal nature of the test.