The Effect of Hyperbaric Oxygen on the Growth of Mucor sp. Aspergillus fumigatus

摘要

Mucor sp. and Aspergillus fumigatus isolated from different human lung infections were observed in vitro for macroscopic and microscopic growth characteristics at varying hyperbaric oxygen levels and for various exposure times and intervals. Both organisms were completely inhibited in oxygen at 3 atmospheres absolute and were at least retarded in all growth processes when subjected to hyperbaric oxygen according to exposure tables routinely used for treating Clostridial gas gangrene. Overall experimental results provide in vitro basis for use of compression chamber therapy in treatment of Mucormycosis and Aspergillosis. (Author)