Preparation, Stability and Acidity of Difluoromethylene Bis Phosphonic Acid

摘要

Hydrolysis of difluoromethylene phosphonate esters quantitatively yields difluoromethylene bis phosphonic acid as a dihydrate. In vacuo drying leads to either the monohydrate or the anhydrous acid. Titration of either the free acid or its disodium salt and computer fit of the data gloves all four pKas. The disodium salt and the free acid are thermally stable, and the disodium salt is extremely stable even to strong base.