Preliminary Assessment of the Relative Toxicity of Copper Naphthenate, (Mooney Chemicals), Acute Studies. Phase 3. May 1984 - October 1987

摘要

A series of studies was performed in laboratory animals and biological systems to determine the relative toxicities of copper naphthenate and a wood preservative formulation thereof (M-Gard W-510, Mooney Chemicals). The studies included primary skin and eye irritation, acute, oral and dermal toxicity, skin sensitization, saturated vapor inhalation, dominant lethal studies, avian toxicity and aquatic toxicity. The results of this testing indicated that M-Gard W-510 has the potential of cause moderate irritation by the dermal route. Copper naphthenate and M-Gard W-510 are of low toxicity by the oral route. High atmospheric concentrations of M-Gard W-510 did cause death in exposed rats. Recommendations provide for the wearing of protective eyewear, gloves and coveralls by the individuals involved in preservative treatment operations and that these operations should be carried out in well ventilated areas. Due to the high degree of toxicity of copper naphthenate in one fish species, it was further recommended that disposal of excess preservative materials should be done in an environmentally acceptable manner. (aw)