Inhibition of Orthopaedic Implant Infections by Immunomodulatory Effects of Host Defense Peptides.

摘要

Host defense peptides represent a promising new approach to inhibit infection. The anti-infective actions of these peptides are primarily due to their immunomodulatory effects. Since they regulate multiple aspects of the mammalian immune system, host defense peptides are also less likely to induce bacterial resistance than are traditional antibiotics.